Jove
Visualize
Contact Us

Related Experiment Videos

Oesophageal transit time evaluated by a biomagnetic method

N A Daghastanli1, F J Braga, R B Oliveira

  • 1Department of Physics and Mathematics-FFCLRP-USP, Ribeirão Preto, SP, Brazil. baffa@biomag.ffclrp.usp.br

Physiological Measurement
|September 15, 1998
PubMed
Summary

Biomagnetic imaging offers a new way to measure oesophageal transit time (OTT), showing a strong correlation with the established scintigraphy method. This technique may provide a valuable alternative for assessing oesophageal function.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A cone-beam optical CT based on a convergent light source - Characterization and optimization.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2024
Same author

Assessing the reaction to and efficacy of the Screener drug discovery and development board game as a pedagogical tool in postgraduate courses.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2024
Same author

Assessment of dosimetric sensitivity enhancement of xylenol orange Fricke gel by AuNPs: optical and MR imaging investigation.

Physics in medicine and biology·2023
Same author

Characterization of novel polydiacetylene gel dosimeter for radiotherapy.

Biomedical physics & engineering express·2021
Same author

High-Fat Diet Induces Disruption of the Tight Junction-Mediated Paracellular Barrier in the Proximal Small Intestine Before the Onset of Type 2 Diabetes and Endotoxemia.

Digestive diseases and sciences·2020
Same author

Preclinical toxicity of innovative molecules: In vitro, in vivo and metabolism prediction.

Chemico-biological interactions·2019
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Gastroenterology
  • Biophysics
  • Medical Imaging

Background:

  • Oesophageal transit time (OTT) is a key metric for evaluating oesophageal motility.
  • Current methods like scintigraphy involve radiation exposure.
  • A non-invasive, radiation-free alternative is desirable for OTT assessment.

Purpose of the Study:

  • To determine oesophageal transit time (OTT) using a novel biomagnetic technique.
  • To compare the accuracy and correlation of the biomagnetic method against scintigraphy.
  • To evaluate the potential of biomagnetic imaging as a diagnostic tool for oesophageal function.

Main Methods:

  • 19 healthy volunteers swallowed a ferrite-labelled yoghurt bolus.
  • Oesophageal transit was monitored using a first-order gradiometer at the furcula and xiphoid process.

Related Experiment Videos

  • Biomagnetic signals were recorded, and OTT calculated from voltage-time plots.
  • Scintigraphy using 99mTc-phytate was performed on the same volunteers for comparison.

    • Main Results:

    • The average OTT by scintigraphy was 3.8 ± 0.8 s.
    • The average OTT by the biomagnetic technique was 4.6 ± 0.9 s.
    • A significant correlation was found between the OTT measurements from both techniques, despite scintigraphy yielding shorter times.

    Conclusions:

    • The biomagnetic technique demonstrates a significant correlation with scintigraphy for measuring oesophageal transit time (OTT).
    • This non-invasive biomagnetic method shows promise as a viable alternative to scintigraphy for evaluating oesophageal motility.
    • Further research can explore its clinical utility in various oesophageal disorders.