Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transcranial magnetic stimulation: language function

C M Epstein1

  • 1Department of Neurology, Emory University School of Medicine and Rehabilitation Research and Development Center, Atlanta VA Medical Center, Georgia, USA.

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
|September 15, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional magnetic resonance imaging and transcranial magnetic stimulation: effects of motor imagery, movement and coil orientation.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2005
Same author

Topics in transcranial magnetic stimulation.

Supplements to Clinical neurophysiology·2003
Same author

Dipoles and dementia.

Journal of neurology, neurosurgery, and psychiatry·2003
Same author

Remission of intractable partial epilepsy following implantation of intracranial electrodes.

Neurology·2001
Same author

Deconvolution of transcranial magnetic stimulation (TMS) maps.

Journal of neural transmission (Vienna, Austria : 1996)·2001
Same author

Magnetic stimulation coil and circuit design.

IEEE transactions on bio-medical engineering·2000
Same journal

Surface EEG to Identify Cognitive Motor Dissociation After Acute Brain Injury.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
Same journal

The Physics and Physiology of Electrical Stimulation of the Brain.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
Same journal

Neurophysiology in Postanoxic Encephalopathy: Pathophysiology, Prognosis, and Treatment.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
Same journal

A Review on the Functional Connectivity of the Human Opercular Cortex.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
Same journal

Surgical Aspects of Opercular Epilepsies.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
Same journal

Cost-Effectiveness of EEG Monitoring in Hypoxic-Ischemic Brain Injury After Cardiac Arrest.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
See all related articles

Transcranial magnetic stimulation (TMS) studies reveal complex language processing. While TMS can temporarily disrupt speech, findings challenge classic language models, showing unexpected lateralization and highlighting TMS

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Neurolinguistics

Background:

  • Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique used to investigate language processing.
  • Previous research focused on identifying language areas and understanding their functions through TMS.
  • TMS can modulate neural activity, either inhibiting or facilitating cognitive processes.

Purpose of the Study:

  • To explore the effects of TMS on language functions, including speech production and comprehension.
  • To investigate the precise cortical regions involved in language processing using TMS.
  • To compare TMS findings with established models of language organization.

Main Methods:

  • Application of rapid-rate TMS over specific cortical regions, particularly the left inferior frontal gyrus.

Related Experiment Videos

  • Observing the effects of TMS on speech output, comprehension, and verbal memory.
  • Comparing TMS-induced effects with results from Wada tests and direct cortical stimulation.

    • Main Results:

    • Rapid-rate TMS over the left inferior frontal region frequently caused speech arrest, but often over the facial motor cortex rather than predicted language areas.
    • True aphasia was rare, with unexpected findings of right hemisphere or bilateral language involvement.
    • Facilitation of language-related tasks (e.g., word association, memory recall) was observed, alongside modulation of motor responses by speech output.

    Conclusions:

    • Current TMS findings challenge traditional models of language localization, suggesting more complex and distributed neural networks.
    • While clinical applications are still developing, TMS offers valuable insights into language organization and function.
    • Further research is needed to fully establish the clinical utility of TMS in language studies.