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DNA issues
1Department of Research, Pasteur Mérieux Connaught, Marcy l'Etoile, France.
Abstract:
For many years the debate surrounding the potential danger of contaminating cellular DNA in biological products has focussed on the possibility that this DNA could give rise to tumours in the recipient host. Current knowledge of the nature and the fate of this DNA after in vivo administration allows us to conclude that this material represents a minimal risk to the patient.