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Synovial chondromatosis: clonal chromosome changes provide further evidence for a neoplastic disorder
R Sciot1, P Dal Cin, J Bellemans
1Department of Pathology, University of Leuven, Belgium.
Virchows Archiv : an International Journal of Pathology
|September 16, 1998
Abstract:
Synovial chondromatosis is a rare lesion, which is still believed by most authors to be reactive rather than neoplastic. We report on a case of synovial chondromatosis with clonal chromosomal changes [43,XX,der (1) t (1;13) (p21-22;q21),-6,-13,-14, add(21) (q21)]. The presence of clonal chromosomal changes in this and in three previously reported cases suggests that synovial chondromatosis is a true neoplastic lesion.