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Related Experiment Videos

Herpes simplex virus

L E Riley1

  • 1Vincent Memorial Obstetrics & Gynecology Service, Massachusetts General Hospital, Boston, USA.

Seminars in Perinatology
|September 17, 1998
PubMed
Summary
This summary is machine-generated.

Herpes simplex virus (HSV) infection poses risks to newborns. Preventing HSV during pregnancy is crucial due to potential severe outcomes for neonates, even from asymptomatic maternal shedding.

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Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Medicine
  • Infectious Diseases

Background:

  • Herpes simplex virus (HSV) infection is a global health concern.
  • HSV can cause significant illness and death in newborns exposed during delivery.
  • Primary herpes vulvovaginitis in pregnant women poses the highest transmission risk to neonates.

Purpose of the Study:

  • To highlight the risks of neonatal herpes simplex virus (HSV) infection.
  • To emphasize the importance of HSV prevention during pregnancy.
  • To inform management strategies for pregnant women with HSV.

Main Methods:

  • Review of current literature on HSV infection in pregnancy and neonates.
  • Analysis of diagnostic methods for HSV infection (serology, viral culture, PCR).

Related Experiment Videos

  • Discussion of clinical presentation and outcomes of neonatal HSV.

    • Main Results:

    • Neonatal HSV can manifest as localized lesions, CNS infection, or disseminated disease.
    • Asymptomatic maternal HSV shedding is a significant route of neonatal transmission.
    • First-episode HSV in late pregnancy carries the greatest risk for neonatal transmission.

    Conclusions:

    • Pregnant women with active HSV lesions at delivery should be considered for cesarean section.
    • Preventive measures against HSV during pregnancy are vital.
    • Early diagnosis and management are critical for improving neonatal outcomes.