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The expression patterns of endothelin-A receptor and endothelin 1 in the avian embryo
V Nataf1, A Grapin-Botton, D Champeval
1Institut d'Embryologie Cellulaire et Moléculaire du Centre National de la Recherche Scientifique et du Collège de France, 49 bis Avenue de la Belle Gabrielle, 94736, Nogent-sur-Marne Cedex, France.
Mechanisms of Development
|September 18, 1998
Abstract:
We investigated the expression pattern of the endothelin-A receptor and endothelin 1 genes, the mutations of which affect the development of the mesectodermal derivatives of the neural crest. We show here that endothelin 1 is expressed by the environment of the cephalic neural crest cells invading branchial arches. Later on, while the neural crest-derived tissues of the head continue to express endothelin-A receptor, endothelin 1 is no longer expressed in their environment.