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Related Experiment Videos

Symptomatic pulmonary hyalinizing granuloma

J Ramirez1, J B Mehta, R A Taylor

  • 1Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City 37614-0622, USA.

Southern Medical Journal
|September 22, 1998
PubMed
Summary
This summary is machine-generated.

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Pulmonary hyalinizing granuloma (PHG) can present as calcified pulmonary nodules and cavitary lesions. Early diagnosis and surgical excision of PHG can resolve chest pain.

Area of Science:

  • Pulmonology
  • Radiology
  • Pathology

Background:

  • A 37-year-old male presented with a 4-week history of left-sided chest pain.
  • Initial workup including physical examination, labs, and ECG was unremarkable.

Observation:

  • Chest X-ray revealed calcified pulmonary nodules.
  • CT scan showed bilateral parenchymal cavitary lesions.
  • Surgical excision of a 2.5-3.0 cm nodule from the left upper lobe was performed.

Findings:

  • Histopathology demonstrated a well-circumscribed lesion with extensive lamellar hyalinization and focal calcification.
  • Pulmonary hyalinizing granuloma (PHG) was diagnosed.
  • Post-operative pain resolved with analgesics.

Implications:

Related Experiment Videos

  • PHG can manifest with cavitating lesions and multifocal calcification.
  • Consider PHG in the differential diagnosis for patients with multiple pulmonary nodules.
  • This case highlights the importance of integrating imaging and histopathology for accurate diagnosis.