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Updated: Aug 27, 2026

Use of a Low-flow Digital Anesthesia System for Mice and Rats
Published on: September 7, 2016
Reinforcing a "low flow" anaesthesia policy with feedback can produce a sustained reduction in isoflurane consumption
1Dept of Anaesthesia and Intensive Care, Palmerston North Hospital, New Zealand.
Abstract:
A three-month audit of isoflurane consumption at Palmerston North Hospital in 1994 showed an averaged vapour flow rate of approx 85 ml per minute of anaesthesia, equivalent to 1.4% isoflurane at six litres per minute. After purchasing volatile agent analysers, a program encouraging low flow anaesthesia and providing a report of the previous month's consumption rate was started in July 1996. The isoflurane averaged vapour flow rate was tracked over the following twenty-month period and fell by a sustained 65% to range around 30 +/- 5 ml/min, producing savings of approximately NZ$104,000 over this period.
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