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[Protective ptosis by botulinum A toxin injection in corneal affectations]
G C Gusek-Schneider1, F Erbguth
1Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg.
Klinische Monatsblatter Fur Augenheilkunde
|September 23, 1998
Summary
Botulinum toxin A injections effectively induce protective ptosis, aiding the healing of persistent corneal ulcers and erosions. This treatment offers a viable alternative to tarsorrhaphy, particularly for patients with potential for facial nerve recovery.
Area of Science:
- Ophthalmology
- Neurology
Context:
- Botulinum toxin A is used for focal muscular hypercontractions.
- Its efficacy in blepharospasm and hemifacial spasm is established.
- Limited reports exist on using botulinum toxin A for protective ptosis in persistent corneal ulcers.
Purpose:
- To evaluate the efficacy of botulinum toxin A-induced protective ptosis in treating persistent corneal erosions and ulcers.
Summary:
- 21 patients with refractory corneal erosions/ulcers received botulinum toxin A injections.
- Induced ptosis led to complete healing in 61.8% of patients.
- Healing rates were higher in younger patients and those with erosions versus ulcers.
Impact:
- Botulinum toxin A injection is an effective alternative to tarsorrhaphy for persistent corneal conditions.
- This method is especially beneficial for patients with lagophthalmos due to facial nerve paresis.
- The treatment demonstrated a good safety profile with minimal side effects.