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Updated: Aug 14, 2026
Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
Published on: December 15, 2014
[Differentiation between benign and malignant breast lesions using fat-suppressed dynamic MR imaging]
T Koshiishi1, I Isomoto, K Nakamura
1Department of Radiology, Saga National Hospital.
Purpose:
To assess the value and problems of fat-suppressed dynamic MR imaging in differentiating between benign and malignant lesions.
Materials And Methods:
In twenty-nine patients who underwent excisional biopsy or surgical resection, fat-suppressed dynamic MR imaging was performed with a 0.5 T superconducting magnet. Pre-and postcontrast 3D-spoiled gradient echo sequences were employed with fat suppression. We calculated and evaluated the contrast-to-noise ratio (CNR) and contrast enhancement ratio (CER) at each contrast determination time (CDT), which is the intermediate time in the scan.
Results:
Time intensity curves of CNR showed no statistically significant difference between cancers and other benign lesions. The difference in CER between malignant and benign disease was highly significant (P = .006) at CDT 45 sec., but there was great overlap in the time intensity curve of CER after CDT 45 sec.
Conclusion:
When we attempt to differentiate malignant from benign breast lesions by dynamic MR imaging, comparison of CNR is impertinent, and we should evaluate the differential diagnosis of cancer versus benign lesions by means of CER at CDT points of about 45 sec.
