[Multiple congenital smooth-muscle hamartomas]

Area of Science:

• Dermatology
• Pediatric Pathology
• Medical Genetics

Background:

• Smooth muscle hamartoma is a rare congenital skin anomaly.
• Typically presents as a solitary plaque with hypertrichosis at birth.
• Multiple plaque presentations are exceptionally uncommon.

Observation:

• A 5-day-old infant presented with multiple, minimally infiltrative plaques.
• Lesions were noted on the buttocks, left lower extremity, shoulder, and right ankle.
• Affected areas were covered with long, dark hair.

Findings:

• Histological examination revealed hyperplastic smooth muscle bundles with varied orientations.
• Diagnosis confirmed as congenital smooth muscle hamartoma.
• The infant had no other significant clinical abnormalities.

Implications:

• This case expands the known spectrum of congenital smooth muscle hamartoma presentations.
• Highlights the possibility of multiple, partially regressive lesions.
• Emphasizes the importance of thorough examination for rare dermatological conditions in neonates.