Relationships among respiratory infections, triggers of attacks, and asthma severity in children

E P Sarafino1, J M Dillon

  • 1The College of New Jersey, Ewing 08628-0718, USA.

Insights

Asthma severity in children is linked to past and recent respiratory infections. Prior infections correlated with more asthma triggers, while recent infections linked to fewer triggers.

Area of Science:

  • Pediatric Pulmonology
  • Environmental Health
  • Epidemiology

Background:

  • Respiratory infections are common in children and may influence asthma development and severity.
  • Asthma triggers vary widely, and their impact can be influenced by individual factors.
  • Understanding the interplay between infections, triggers, and asthma severity is crucial for effective management.

Purpose of the Study:

  • To investigate the relationships between prior and recent respiratory infections, asthma severity, and the impact of common asthma triggers in children.
  • To determine which asthma triggers are most strongly associated with infection history and asthma severity.
  • To provide insights into the multifactorial nature of childhood asthma.

Main Methods:

  • A survey was administered to 325 families, including 121 families with asthmatic children aged 2-20 years.
  • Data collected included frequencies of prior and recent respiratory infections, asthma severity, and the perceived impact of 12 common asthma triggers.
  • Pearson correlational analyses were employed to examine the relationships among these variables.

Main Results:

  • Significant positive correlations were found between the frequencies of prior and recent respiratory infections.
  • Prior infections correlated with the impact of most asthma triggers (except allergies), while recent infections correlated with fewer triggers (air pollution, smoke, respiratory infection, nighttime).
  • Asthma severity showed correlations with both prior and recent respiratory infections, and specifically with respiratory infection as a trigger.

Conclusions:

  • Both the history of respiratory infections and recent infections play a role in childhood asthma.
  • The impact of various asthma triggers on asthma attacks is influenced by the frequency of past and recent respiratory infections.
  • Respiratory infection itself is a significant trigger, particularly in relation to asthma severity.

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