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Published on: August 7, 2017
Relationships among respiratory infections, triggers of attacks, and asthma severity in children
1The College of New Jersey, Ewing 08628-0718, USA.
Insights
Asthma severity in children is linked to past and recent respiratory infections. Prior infections correlated with more asthma triggers, while recent infections linked to fewer triggers.
Area of Science:
- Pediatric Pulmonology
- Environmental Health
- Epidemiology
Background:
- Respiratory infections are common in children and may influence asthma development and severity.
- Asthma triggers vary widely, and their impact can be influenced by individual factors.
- Understanding the interplay between infections, triggers, and asthma severity is crucial for effective management.
Purpose of the Study:
- To investigate the relationships between prior and recent respiratory infections, asthma severity, and the impact of common asthma triggers in children.
- To determine which asthma triggers are most strongly associated with infection history and asthma severity.
- To provide insights into the multifactorial nature of childhood asthma.
Main Methods:
- A survey was administered to 325 families, including 121 families with asthmatic children aged 2-20 years.
- Data collected included frequencies of prior and recent respiratory infections, asthma severity, and the perceived impact of 12 common asthma triggers.
- Pearson correlational analyses were employed to examine the relationships among these variables.
Main Results:
- Significant positive correlations were found between the frequencies of prior and recent respiratory infections.
- Prior infections correlated with the impact of most asthma triggers (except allergies), while recent infections correlated with fewer triggers (air pollution, smoke, respiratory infection, nighttime).
- Asthma severity showed correlations with both prior and recent respiratory infections, and specifically with respiratory infection as a trigger.
Conclusions:
- Both the history of respiratory infections and recent infections play a role in childhood asthma.
- The impact of various asthma triggers on asthma attacks is influenced by the frequency of past and recent respiratory infections.
- Respiratory infection itself is a significant trigger, particularly in relation to asthma severity.
Abstract:
The present study of asthmatic children examined relationships among the frequencies of prior respiratory infections (i.e., those prior to the development of asthma) and recent (past year) respiratory infections, asthma severity, and the impacts of 12 common asthma triggers: air pollution, allergy problems, anger, cigarette smoke, excitement, high humidity, high or low environmental temperature, laughter, nighttime hours, physical activity, respiratory infection, and stress or worry. Data on these variables were obtained through a survey in which 325 families completed questionnaires; 121 families had asthmatic children who were 2-20 years of age. Pearson correlational analyses revealed many significant positive correlations: The frequencies of prior and recent infections were correlated. The frequency of prior infections was correlated with the impacts of all asthma triggers except allergy problems, but the frequency of recent infections was correlated only with the impacts of air pollution, cigarette smoke, respiratory infection, and nighttime hours as triggers of asthma attacks. Asthma severity was correlated with the frequencies of prior and recent respiratory infections and with the impact of respiratory infection as an asthma trigger.
Related Concept Videos
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-I: Introduction
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-III: Symptoms and Complications
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Asthma I: Introduction
Asthma III: Clinical Manifestations

