[Severe tardive dyskinesia during treatment with risperidone and fluoxetine]

A 26-year-old man with schizophrenia, disorganised type, and depression, developed severe tardive dyskinesia during treatment with risperidone and fluoxetine. In view of the course of the symptoms and the findings in the neurological analysis a causal relation with the use of the these second-generation psychopharmaca was probable. These new-generation psychopharmaca are supposed to have fewer adverse events. Nevertheless, as is illustrated in this case, prescription is not without risk. Especially when using a combination of psychopharmaca, side effects must be monitored carefully.