[An endoscopic treatment alternative in vesico-ureteral reflux (VUR)]

Vesicoureteral reflux (VUR) represent an important pathology (surgical treatment was until recently the "gold standard" therapy) in urology. Between September 1995 and October 1997 we used endoscopic Romanian collagen injection in 21 cases with VUR (3 cases grade II, 14 cases grade III, 4 cases grade IV). The collagen solution (1/1 with distilled water) was injected at the 6 hour of the ureteral large ostium (15/35 ml). In some cases we obtained the perfect occlusion of the incompetent ureteral ostium by complementary injections at 3 and 9 hours. It was necessary to reinject collagen twice in 8 cases and three times in 3 cases. Success rate appeared in 66.66% cases. We did not confront ourselves with postoperative complications. Hospitalization period was 3.2 days. The mean follow-up period was 12 months (range 6 to 28). Our results prove that endoscopic collagen injection applied in VUR is a simple, efficient, without complications method, minimally invasive.