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Updated: Aug 11, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
Published on: November 8, 2012
Mechanisms of directed attention in the human extrastriate cortex as revealed by functional MRI
S Kastner1, P De Weerd, R Desimone
1Laboratory of Brain & Cognition, National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Building 49, Room 1B80, Bethesda, MD 20892-4415, USA. sabine@ln.nimh.nih.gov
Abstract:
A typical scene contains many different objects, but the capacity of the visual system to process multiple stimuli at a given time is limited. Thus, attentional mechanisms are required to select relevant objects from among the many objects competing for visual processing. Evidence from functional magnetic resonance imaging (MRI) in humans showed that when multiple stimuli are present simultaneously in the visual field, their cortical representations within the object recognition pathway interact in a competitive, suppressive fashion. Directing attention to one of the stimuli counteracts the suppressive influence of nearby stimuli. This mechanism may serve to filter out irrelevant information in cluttered visual scenes.
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