Related Experiment Videos
[Therapy of nail mycoses]
1Dermatologische Universitätsklinik, Kantonsspital Basel.
Therapeutische Umschau. Revue Therapeutique
|October 3, 1998
Summary
Onychomycosis, a common fungal nail infection, requires personalized treatment. Newer oral antifungals like terbinafine offer effective options, often combined with topical treatments for better outcomes.
Area of Science:
- Dermatology
- Mycology
- Pharmacology
Background:
- Onychomycosis is the most prevalent nail disease, constituting 30% of cutaneous fungal infections.
- Effective treatment necessitates consideration of disease extent, drug sensitivity, patient factors, and medication interactions.
Purpose of the Study:
- To outline the diagnostic and therapeutic strategies for managing onychomycosis.
- To review the role of newer oral and topical antifungal agents in onychomycosis treatment.
Main Methods:
- Review of diagnostic methods including direct microscopy and fungal culture.
- Analysis of treatment considerations: drug selection, patient-specific factors, and combination therapies.
Main Results:
- Accurate diagnosis relies on appropriate specimen collection from the affected nail site.
- Topical antifungals are suitable for early cases without nail matrix involvement.
- Oral agents like terbinafine, itraconazole, and fluconazole are key treatments, often used with topicals.
Conclusions:
- Personalized treatment plans are crucial for onychomycosis management.
- Newer oral and topical antifungal combinations provide effective therapeutic options for most patients.