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Related Experiment Videos

Perioperative hypertension

M E Goldberg1, G E Larijani

  • 1Department of Anesthesiology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Health System, USA.

Pharmacotherapy
|October 3, 1998
PubMed
Summary
This summary is machine-generated.

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Perioperative hypertension, often caused by autonomic nervous system imbalance, is treated to balance heart oxygen supply and demand. Newer drugs like nicardipine and fenoldopam are considered, but long-term outcome data is lacking.

Area of Science:

  • Anesthesiology
  • Cardiovascular Medicine
  • Pharmacology

Background:

  • Perioperative hypertension frequently results from autonomic nervous system overactivity or insufficient inhibition.
  • Maintaining myocardial oxygen supply and demand balance is a primary treatment objective.
  • Current treatment strategies for perioperative hypertension are aggressively applied.

Purpose of the Study:

  • To evaluate the role of newer agents in managing perioperative hypertension.
  • To consider the cost-benefit implications of novel therapeutic options.
  • To assess the impact of perioperative hypertension treatment on long-term patient outcomes.

Main Methods:

  • Review of current literature on perioperative hypertension management.
  • Analysis of potential advantages of newer agents (nicardipine, fenoldopam) versus older agents.

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  • Consideration of the cost-effectiveness of different therapeutic approaches.

    • Main Results:

    • Newer agents like nicardipine and fenoldopam present potential benefits in managing perioperative hypertension.
    • The cost-benefit ratio of these newer agents requires careful evaluation.
    • Despite aggressive treatment, conclusive long-term study data on patient outcomes is currently unavailable.

    Conclusions:

    • While newer agents offer promise, their clinical and economic value needs further investigation.
    • The long-term impact of aggressively treating perioperative hypertension on patient outcomes remains uncertain.
    • Further large-scale studies are necessary to guide evidence-based treatment decisions.