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Transthoracic echocardiographic measurement of coronary artery diameter: validation against quantitative coronary

D J Hildick-Smith1, L M Shapiro

  • 1Department of Cardiology, Papworth Hospital, Cambridgeshire, England, UK.

Insights

Transthoracic echocardiography is a valid method for measuring distal left anterior descending (LAD) coronary artery diameter. This non-invasive technique showed good correlation with quantitative coronary angiography in male patients.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Vascular Ultrasound

Background:

  • Invasive methods like cardiac catheterization are standard for assessing coronary artery diameter.
  • Non-invasive validation of transthoracic echocardiography for distal left anterior descending (LAD) coronary artery diameter measurement is lacking.
  • Accurate measurement of LAD diameter is crucial for diagnosing and managing coronary artery disease.

Purpose of the Study:

  • To validate the use of transthoracic echocardiography (TTE) for measuring distal left anterior descending (LAD) coronary artery diameter in vivo.
  • To compare TTE measurements with quantitative coronary angiography (QCA) findings.
  • To establish the reliability and accuracy of TTE for distal LAD diameter assessment.

Main Methods:

  • Transthoracic echocardiography was performed on 65 male patients prior to cardiac catheterization.
  • The distal LAD was successfully imaged in 41 patients.
  • Measurements from TTE were compared with those obtained from QCA in 29 patients with angiographically normal distal LAD.

Main Results:

  • The distal LAD was successfully visualized using TTE in 63% of patients.
  • Echocardiographic measurements of distal LAD diameter ranged from 0.14 to 0.28 cm (mean 0.20 cm).
  • Angiographic measurements ranged from 0.12 to 0.28 cm (mean 0.195 cm), showing good correlation (r=0.925) with TTE.
  • The maximum discrepancy between TTE and QCA was 0.03 cm, with limits of agreement of +0.032 to -0.024 cm.

Conclusions:

  • Transthoracic echocardiography is a valid and reliable non-invasive technique for measuring distal left anterior descending coronary artery diameter.
  • TTE offers a comparable alternative to QCA for assessing distal LAD diameter, with good accuracy.
  • This validation supports the potential use of TTE in clinical settings for evaluating the distal LAD.

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