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Updated: Jul 20, 2026

Enhanced Rabies Surveillance Using a Direct Rapid Immunohistochemical Test
Published on: April 30, 2019
[Rabies is a risk for travelling children]
1Centre national de référence pour la rage, Institut Pasteur, Paris, France.
Insights
Rabies is a deadly disease killing 50,000 annually, especially children. Pre-exposure vaccination is crucial for children traveling to endemic areas to prevent rabies.
Area of Science:
- Public Health
- Infectious Diseases
- Vaccinology
Context:
- Rabies causes approximately 50,000 deaths yearly, disproportionately affecting children in Asia, Africa, South America, and Central Europe.
- Modern rabies vaccines are both safe and effective in generating immunity.
- The disease poses a significant threat, particularly in regions with endemic canine rabies populations.
Purpose:
- To inform parents about the risks of rabies and the importance of vaccination for children.
- To advocate for pre-exposure vaccination for children with frequent or extended travel to rabies-enzootic regions.
- To emphasize the necessity of prompt post-exposure treatment with modern vaccines.
Summary:
- Rabies remains a significant global health concern, with a high mortality rate, especially among young children.
- The availability of safe and immunogenic modern rabies vaccines necessitates informed parental decisions regarding travel and vaccination.
- Timely post-exposure prophylaxis is critical, and pre-exposure vaccination offers a vital protective measure, particularly in resource-limited settings.
Impact:
- Increased awareness among parents regarding rabies risks and vaccination benefits.
- Potential reduction in pediatric rabies cases through informed vaccination strategies.
- Improved management of rabies exposure through timely and appropriate medical intervention.
Abstract:
Rabies remains a dreadful disease which kills about 50,000 people per year, mostly in Asia, Africa, South America and Central Europe. Between 30% an 50% of the victims are young children. Modern rabies vaccines are safe and immunogenic. Therefore parents must be informed on the risk of rabies, and pre-exposure vaccination must be performed for children traveling often or for periods longer than one month in canine enzootic countries. Post-exposure treatment must be initiated without delay with modern vaccines wherever available, according to approved schedules. Pre-exposure vaccination is particularly useful in remote places where modern vaccines and immunoglobulins are not readily available.
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