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Vulvar intraepithelial neoplasia and carcinoma
1Gynecological Cancer Center, Royal Hospital for Women, Randwick, Sydney, Australia.
Abstract:
This report describes the classification, clinical profile, etiology, and management of high-grade squamous vulvar intraepithelial-neoplasia (VIN). Recent studies have better defined the progressive potential of high-grade VIN and the relationship of such lesions to squamous vulvar carcinoma. The histologic classification and descriptions have undergone significant refinement over the past decade. The increasing use of more conservative therapeutic approaches to high-grade VIN has demanded greater expertise in clinical evaluation to ensure invasive disease is not missed or undertreated.
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