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Do routine antibiotics after loop diathermy excision reduce morbidity?
J Foden-Shroff1, C W Redman, H Tucker
1Department of Obstetrics and Gynaecology, North Staffordshire Hospital NHS Trust, Harpfields, Stoke on Trent, UK.
Objective:
To evaluate whether routinely giving an antibiotic after loop diathermy excision of the cervical transformation zone reduced post-operative vaginal loss.
Design:
Prospective, randomised, double-blind placebo controlled parallel study.
Participants:
Five hundred women undergoing loop diathermy excision in a colposcopy clinic.
Intervention:
Administration of either ofloxacin 400 mg (2x200 mg) once daily for 5 days or an identical placebo.
Main Outcome Measure:
Vaginal loss, assessed using a pictorial chart.
Results:
No significant difference in post-operative vaginal loss was found.
Conclusion:
Routine antibiotic prophylaxis after loop diathermy excision is not justified.
