Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Do routine antibiotics after loop diathermy excision reduce morbidity?

J Foden-Shroff1, C W Redman, H Tucker

  • 1Department of Obstetrics and Gynaecology, North Staffordshire Hospital NHS Trust, Harpfields, Stoke on Trent, UK.

British Journal of Obstetrics and Gynaecology
|October 8, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Benign functional anorectal conditions: a multi-centre analysis of rectal stump symptomatology in patients undergoing stoma formation.

Techniques in coloproctology·2026
Same author

HLA-DR is aberrantly expressed at feto-maternal interface in pre-eclampsia.

Journal of reproductive immunology·2018
Same author

Angiogenic factors: potential to change clinical practice in pre-eclampsia?

BJOG : an international journal of obstetrics and gynaecology·2017
Same author

Genetics and genetic testing for age-related macular degeneration.

Eye (London, England)·2017
Same author

Trophoblast Glycoprotein (TPGB/5T4) in Human Placenta: Expression, Regulation, and Presence in Extracellular Microvesicles and Exosomes.

Reproductive sciences (Thousand Oaks, Calif.)·2017
Same author

Problems and solutions in delivering global surgery in the 21st century.

The British journal of surgery·2015
Same journal

Livial: an economic appraisal.

British journal of obstetrics and gynaecology·2000
Same journal

Livial: a review of clinical studies.

British journal of obstetrics and gynaecology·2000
Same journal

Place of birth and shoulder dystocia.

British journal of obstetrics and gynaecology·1999
Same journal

The value of the negative predictive values.

British journal of obstetrics and gynaecology·1999
Same journal

Splenectomy during pregnancy: an option in treatment of autoimmune thrombocytopenic purpura.

British journal of obstetrics and gynaecology·1999
Same journal

Third trimester abortion: is compassion enough?

British journal of obstetrics and gynaecology·1999
See all related articles

Routine antibiotic prophylaxis after loop diathermy excision does not significantly reduce post-operative vaginal loss. This study found no difference in blood loss between women receiving antibiotics or a placebo, suggesting it is not routinely justified.

Area of Science:

  • Gynecology
  • Surgical Oncology
  • Infectious Disease Prevention

Background:

  • Loop diathermy excision is a common procedure for treating cervical abnormalities.
  • Post-operative vaginal bleeding is a potential complication.
  • Antibiotic prophylaxis is sometimes used to prevent infection and reduce bleeding.

Purpose of the Study:

  • To determine if routine antibiotic administration after loop diathermy excision of the cervical transformation zone decreases post-operative vaginal blood loss.

Main Methods:

  • A prospective, randomized, double-blind, placebo-controlled parallel study was conducted.
  • 500 women undergoing loop diathermy excision received either ofloxacin or a placebo for 5 days.
  • Vaginal blood loss was quantified using a pictorial chart.

Related Experiment Videos

Main Results:

  • No statistically significant difference in the amount of post-operative vaginal blood loss was observed between the antibiotic and placebo groups.
  • The study did not find evidence to support the routine use of antibiotics to manage vaginal blood loss post-procedure.

Conclusions:

  • Routine antibiotic prophylaxis following loop diathermy excision of the cervical transformation zone is not clinically justified.
  • Current evidence does not support the use of antibiotics solely for reducing post-operative vaginal blood loss in this context.