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[Deep cerebral venous thrombosis]

C Magni1, J Mocaer, P Yapo

  • 1Service de Neuroradiologie, CHR Orléans.

Journal of Neuroradiology = Journal De Neuroradiologie
|October 9, 1998
PubMed
Summary

Deep cerebral venous system thrombosis is rare in adults but treatable. Advances in MRI and heparin therapy offer favorable outcomes, even in severe cases.

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Area of Science:

  • Neurology
  • Vascular Medicine

Background:

  • Deep cerebral venous system thrombosis (DCVT) is a rare condition, predominantly seen in neonates.
  • Its occurrence in adults is exceptional, with a higher incidence in women using oral contraceptives.

Observation:

  • The typical presentation involves headaches and confusion, with coma being infrequent.
  • Two adult cases are presented, highlighting the rarity and clinical spectrum of DCVT.

Findings:

  • Diagnosis relies on CT scans, but MRI with MR angiography (MRA) is definitive.
  • MRI is most effective for subacute thrombus detection; MRA is crucial in the acute phase.
  • Heparin is the primary treatment, with potential roles for local thrombolytics.

Implications:

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  • Despite a historically poor prognosis, modern diagnostic and therapeutic strategies improve outcomes.
  • Early diagnosis and treatment, particularly with anticoagulation, can lead to recovery without sequelae.
  • Further research is needed to establish the role of local thrombolytic therapy.