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Encouraging response of an advanced steroid-cell tumor to GnRH agonist therapy
1Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, and St. John's Hospital, Springfield 62794-1315, USA.
Obstetrics and Gynecology
|October 9, 1998
Abstract
Background:
Chemotherapy for steroid tumors of unspecified type has met with limited success and the overall prognosis has been poor.
Case:
A patient with a virilizing steroid tumor, otherwise unspecified, with demonstrated progressive disease after surgical debulking. Treatment with multiagent chemotherapy failed, but the patient subsequently had a robust response to GnRH agonist therapy.
Conclusion:
GnRH analogue treatment should be considered prior to cytotoxic chemotherapy in cases of steroid tumor, not otherwise specified.