Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic tophaceous gout in the elderly

J M van der Klooster1, R Peters, J P Burgmans

  • 1Department of Internal Medicine, St. Clara Ziekenhuis, Rotterdam, The Netherlands.

The Netherlands Journal of Medicine
|October 10, 1998
PubMed
Summary

Gout in elderly patients presents atypically, complicating treatment. This study highlights two cases of severe tophaceous gout causing deformities, emphasizing diagnostic methods and management challenges in older adults.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nano-org, a functional resource for single-molecule localisation microscopy data.

Nature communications·2025
Same author

Target organ toxicity in Sprague Dawley rats following oral exposure to complex groundwater mixture: Assessment of dose-response relationships using histopathological and biochemical alterations.

Regulatory toxicology and pharmacology : RTP·2024
Same author

Impaired memory in Sprague-Dawley rats exposed to complex groundwater mixtures of contaminants is associated with reduced cranial blood flow and hippocampal neurotoxicity.

Neurotoxicology·2024
Same author

Herbicides and pesticides synergistically interact at low concentrations in complex mixtures.

Chemosphere·2024
Same author

Validation of the CogDrisk Instrument as Predictive of Dementia in Four General Community-Dwelling Populations.

The journal of prevention of Alzheimer's disease·2023
Same author

Mobility of Membrane Lipids and Proteins at the Animal and Vegetal Pole of the Sea Urchin Egg: (sea urchin/polarity/plasma membrane/translational mobility/fluorescence microphotolysis, photobleaching).

Development, growth & differentiation·2023

Area of Science:

  • Rheumatology
  • Geriatric Medicine

Background:

  • Gout in the elderly is a distinct clinical subgroup.
  • Atypical presentations and treatment challenges are common in geriatric gout patients.

Observation:

  • Two elderly patients presented with large subcutaneous tophi causing significant deformities.
  • Clinical features, risk factors, diagnosis, and treatment were analyzed.

Findings:

  • Subcutaneous tophi and radiographic changes are characteristic of tophaceous gout.
  • Definitive diagnosis relies on aspiration and crystal analysis.

Implications:

  • Understanding atypical gout presentations in the elderly is crucial for timely diagnosis.
  • Effective management strategies are needed for tophaceous gout in geriatric populations.

Related Experiment Videos