Lymphocytic hypophysitis in a 43-year-old woman

A woman with sarcoidosis and primary hypothyroidism presented with partial hypopituitarism without pituitary gland enlargement. A clinical diagnosis of lymphocytic hypophysitis was established after exclusion of other possibilities, since a definitive diagnosis can only be made after histological studies. This rare form of chronic inflammation and destruction of the anterior pituitary gland is discussed.