Juvenile polyp in esophageal colon interposition
Related Experiment Video
Updated: Oct 28, 2026

Conditional Reprogramming of Pediatric Human Esophageal Epithelial Cells for Use in Tissue Engineering and Disease Investigation
Published on: March 22, 2017
M A Del Rosario1, J M Croffie, F J Rescorla
1Division of Pediatric Gastroenterology, James Whitcomb Riley Hospital for Children, Indianapolis, IN 46202, USA.
Insights
Esophageal polyps are rare in children. A juvenile polyp was found in a surgically repositioned colon segment, suggesting colonic cells may influence polyp development.
Area of Science:
- Pediatric Gastroenterology
- Surgical Pathology
- Gastrointestinal Oncology
Background:
- Esophageal polyps are uncommon in pediatric patients.
- Colorectal juvenile polyps are a frequent finding in children.
- Esophageal strictures can necessitate surgical interventions like colonic interposition.
Observation:
- An 11-year-old male presented with a polypoid mass within an interposed colonic segment.
- The colonic interposition was performed to treat an esophageal stricture caused by caustic injury.
- The patient underwent successful endoscopic removal of the mass via diathermy.
Findings:
- Histological examination confirmed the polyp to be a juvenile polyp.
- This is a rare occurrence of a juvenile polyp in a colon segment outside its native anatomical location.
- The colon segment was serving a new function as a substitute esophagus.
Implications:
- The presence of a juvenile polyp in an ectopic colonic segment suggests a potential role for intrinsic colonic cellular factors in polypogenesis.
- Further research may elucidate unknown factors produced by colonic cells that contribute to juvenile polyp development.
- This case highlights the importance of continued surveillance and understanding of neoplastic potential even in surgically altered gastrointestinal segments.
Abstract:
Esophageal polyps are rare in children, whereas colorectal juvenile polyps are common. An 11-year-old boy with an esophageal colonic interposition for an esophageal stricture secondary to caustic injury was found to have a polypoid mass in the interposed colon. Fiberoptic endoscopic removal with diathermy was performed. Histological examination confirmed it was a juvenile polyp. The occurrence of a polyp in a colon removed from its natural location and serving a different function suggests the possibility that an unknown factor produced by colonic cells play a pivotal role in its development.
Related Concept Videos
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
Esophagus
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Esophageal Varices-I: Introduction
Esophageal Achalasia
