Peptic ulcer in diabetes mellitus

Area of Science:

• Gastroenterology
• Endocrinology
• Internal Medicine

Background:

• Peptic ulcer disease is a common gastrointestinal condition.
• Diabetes mellitus is a metabolic disorder with potential systemic complications.
• The relationship between diabetes and peptic ulcer disease requires further investigation.

Purpose of the Study:

• To determine the incidence of peptic ulcers in hospitalized patients with diabetes mellitus.
• To investigate the correlation between diabetes duration, glycemic control, and gastric ulcer development and severity.

Main Methods:

• Retrospective analysis of 165 hospitalized diabetic patients.
• Identification and characterization of peptic ulcer cases within the cohort.
• Comparison of ulcer characteristics based on diabetes control and duration.

Main Results:

• Twelve cases (7.3%) of peptic ulcer were identified among 165 diabetic patients.
• All identified ulcers were gastric ulcers; no duodenal ulcers were observed.
• Gastric ulcers in poorly controlled diabetic patients exhibited greater intractability compared to those with well-controlled diabetes.

Conclusions:

• The incidence of peptic ulcer disease, particularly gastric ulcers, appears higher in hospitalized diabetic patients than previously reported.
• No significant correlation was found between the duration of diabetes and the onset of gastric ulcers.
• Poor glycemic control in diabetic patients is associated with more intractable gastric ulcers.