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Chronic staphylococcal scalded skin syndrome
E D Shelley1, W B Shelley, N Y Talanin
1Division of Dermatology, Department of Medicine, Medical College of Ohio, PO Box 10008, Toledo, OH 43699-0008, USA.
The British Journal of Dermatology
|October 10, 1998
Summary
A 50-year-old woman experienced a rare 2-year Staphylococcal scalded skin syndrome (SSSS) case, evolving from other skin conditions. Staphylococcus aureus was identified, suggesting potential links between epilepsy and chronic SSSS.
Area of Science:
- Dermatology
- Infectious Diseases
- Neurology
Background:
- Staphylococcal scalded skin syndrome (SSSS) is typically an acute condition.
- Chronic SSSS is exceptionally rare, with limited documentation in adult cases.
Observation:
- A 50-year-old female patient with epilepsy and cerebellar ataxia presented with a persistent skin condition over two years.
- Initial lesions resembled erythema multiforme and toxic epidermal necrolysis, evolving into characteristic SSSS with subcorneal blisters.
Findings:
- Exfoliatin A-producing Staphylococcus aureus was isolated from ocular, auricular, and cutaneous discharge.
- This specific bacterial strain was previously associated only with mild, acute SSSS in adults.
Implications:
- This case challenges the perception of SSSS as exclusively acute, presenting a chronic manifestation.
- Epilepsy and its treatments are explored as potential contributing factors to the prolonged SSSS course.
- The findings broaden the understanding of SSSS pathogenesis and patient risk factors.