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[Late potentials in chronic alcoholics]

G Pochmalicki1, M Genest, A Jibril

  • 1Service de Cardiologie, Centre Hospitalier Général Léon Binet, Provins.

Presse Medicale (Paris, France : 1983)
|October 13, 1998
PubMed
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Late potentials, indicative of myocardial damage, are frequently detected in chronic alcoholics. This finding suggests their potential use in identifying individuals at risk of cardiac arrest and ventricular dysrhythmia.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Toxicology

Background:

  • Cardiac arrest is a leading cause of mortality in chronic alcoholics.
  • Early detection of myocardial disorders and ventricular dysrhythmia risk is crucial in this population.

Purpose of the Study:

  • To investigate the presence and significance of late potentials in chronic alcoholics.
  • To explore the correlation between late potentials and alcohol abuse duration, liver conditions, and laboratory markers.

Main Methods:

  • A prospective study involving 53 chronic alcohol abusers after a period of abstinence.
  • Evaluations included liver tests, liver biopsy, electrocardiogram, echocardiography, and Holter monitoring.

Main Results:

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  • 37% of patients showed positive criteria for late potentials.
  • A significant correlation was found between alcohol abuse duration and the presence of late potentials (p = 0.006).
  • Late potentials were associated with higher hepatic steatosis and abnormal liver function tests (GGT, AST, ALP).

    • Conclusions:

    • Late potentials are detectable in chronic alcoholics.
    • They may serve as an early, infraclinical marker of myocardial damage.
    • Further research is needed to establish the prognostic value of late potentials in this cohort.