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[Lactobacillus acidophilus endocarditis]

J P Penot1, P Lagrange, N Darodes

  • 1Service de Cardiologie, CHU Dupuytren, Limoges.

Presse Medicale (Paris, France : 1983)
|October 13, 1998
PubMed
Summary
This summary is machine-generated.

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Lactobacillus endocarditis is rare but serious, often affecting prosthetic valves. Treatment is challenging due to germ resistance, requiring high-dose antibiotics and surgery.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Cardiology

Background:

  • Lactobacillus species are common commensals in humans.
  • While typically benign, Lactobacillus can cause severe infections like endocarditis, particularly in individuals with prosthetic heart valves.
  • Dental caries are a common manifestation of Lactobacillus pathogenicity.

Observation:

  • A case of Lactobacillus endocarditis in a 70-year-old woman with an aortic valve bioprosthesis is presented.
  • Lactobacillus acidophilus was identified in blood cultures and from the prosthetic valve post-surgery.
  • This highlights a rare but significant clinical presentation of Lactobacillus infection.

Findings:

  • Forty-four cases of Lactobacillus endocarditis have been documented.

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  • The mortality rate for Lactobacillus endocarditis is notably high at 26%.
  • A significant challenge in treatment is the inherent tolerance of Lactobacillus to penicillin and aminoglycosides, observed in all reported cases.

    • Implications:

    • Effective treatment of Lactobacillus endocarditis necessitates high-dose parenteral antibiotic therapy.
    • Surgical intervention is frequently required for successful treatment, occurring in 26% of cases.
    • This underscores the importance of considering Lactobacillus in the differential diagnosis of culture-negative endocarditis, especially in patients with prosthetic valves or risk factors.