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[Diffuse digestive tract B-cell lymphoma manifesting as exudative enteropathy]
S Vinzio1, B Goichot, E Krebs-Wurtz
1Service de Médecine interne, Hôpital de Hautepierre, Strasbourg.
Summary
This case study highlights a rare instance of diffuse digestive tract lymphoma presenting with severe diarrhea and hypoalbuminemia. Treatment with chemotherapy led to a favorable clinical response, suggesting its efficacy in managing this unusual presentation.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Primary lymphomas of the digestive tract typically present with general symptoms and abdominal pain.
- Diarrhea is an uncommon symptom in digestive tract lymphomas and can arise from various mechanisms.
Observation:
- A 68-year-old woman presented with severe diarrhea and hypoalbuminemia, with no evidence of malabsorption or infection.
- Digestive tract biopsies revealed diffuse mucosal invasion by MALT type B-cell lymphoma.
Findings:
- The patient's condition improved significantly following chemotherapy.
- Diffuse gastrointestinal involvement by MALT lymphoma, leading to exudative enteropathy, is exceptionally rare.
Implications:
- This case underscores the importance of considering lymphoma in patients with unexplained diarrhea and hypoalbuminemia.
- The successful chemotherapy response suggests a viable treatment option for this rare presentation of diffuse digestive tract lymphoma.