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[Synthesis and pharmacologic study of 1,5-benzodiazepine-2,4-diones and their alkyl derivatives]
A Zellou1, Y Cherrah, M Hassar
1Laboratoire de Pharmacologie et de Toxicologie, Faculté de Médecine et de Pharmacie, Rabat Instituts, Maroc.
Annales Pharmaceutiques Francaises
|October 14, 1998
Abstract:
From the pharmacodynamic studies of 1,5-benzodiazepin-2,4-diones and alkyl derivatives prepared in our laboratories, we can conclude that these products are not toxic at therapeutic dosage. They have sedative, myorelaxant and anxiolytic actions. The two products alkylated by allyl bromide have also hypnotic, sedative and anticonvulsant properties.