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Parity as a risk factor for cancer cervix
V Gawande1, S N Wahab, S P Zodpey
1Dept. of Preventive and Social Medicine, Govt. Medical College, Nagpur.
Indian Journal of Medical Sciences
|October 15, 1998
Summary
High parity, defined as multiple previous pregnancies, is a significant risk factor for cervical cancer. This finding highlights the potential for interventions targeting multiparity to prevent cervical cancer.
Area of Science:
- Gynecology
- Oncology
- Epidemiology
Background:
- Cervical cancer remains a significant global health concern.
- The role of parity, specifically high parity (multiparity), as a risk factor for cervical cancer requires further investigation.
- Understanding risk factors is crucial for developing effective prevention strategies.
Purpose of the Study:
- To investigate the association between parity and the outcome of cervical cancer.
- To determine if multiparity is a significant risk factor for developing cervical cancer.
- To estimate the attributable risk proportion (ARP) and population attributable risk proportion (PARP) associated with multiparity in cervical cancer.
Main Methods:
- A hospital-based, group-matched case-control study was conducted.
- The study included 230 cases of cervical cancer and 230 age-matched controls.
- Data were collected and analyzed to assess the role of parity.
Main Results:
- Multiparity was identified as a significant risk factor for cervical cancer.
- Estimates of attributable risk proportion (ARP) indicated the etiological role of multiparity.
- Population attributable risk proportion (PARP) estimates suggested a preventable role for multiparity in cervical cancer outcomes.
Conclusions:
- Multiparity is a significant risk factor contributing to the development of cervical cancer.
- The findings support the etiological role of multiparity in cervical cancer.
- Interventions addressing multiparity could play a role in preventing cervical cancer.