Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Inflammatory bowel diseases in children]

E Langholz1, P Munkholm, P A Krasilnikoff

  • 1Amtssygehuset i Herlev, medicinsk gastroenterologisk afdeling C.

Ugeskrift for Laeger
|October 15, 1998
PubMed
Summary

Pediatric inflammatory bowel disease (IBD) incidence is low, with children experiencing more extensive ulcerative colitis (UC) at diagnosis. Crohn's disease (CD) in children shows similar outcomes to adults, though growth issues are noted.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ENDOCRINE DISTURBANCES IN PARASELLAR MENINGIOMAS AND THE EFFECT OF TRANSSPHENOIDAL DECOMPRESSION OPERATIONS.

Acta endocrinologica (Bucharest, Romania : 2005)·2026
Same author

Dietary risk factors for inflammatory bowel diseases in a high-risk population: Results from the Faroese IBD study.

United European gastroenterology journal·2019
Same author

Inflammatory bowel diseases in Faroese-born Danish residents and their offspring: further evidence of the dominant role of environmental factors in IBD development.

Alimentary pharmacology & therapeutics·2017
Same author

Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target.

The American journal of gastroenterology·2015
Same author

Treatment Steps, Surgery, and Hospitalization Rates During the First Year of Follow-up in Patients with Inflammatory Bowel Diseases from the 2011 ECCO-Epicom Inception Cohort.

Journal of Crohn's & colitis·2015
Same author

Deviations in human gut microbiota: a novel diagnostic test for determining dysbiosis in patients with IBS or IBD.

Alimentary pharmacology & therapeutics·2015

Area of Science:

  • Pediatric Gastroenterology
  • Epidemiology of Inflammatory Bowel Disease

Background:

  • Inflammatory Bowel Disease (IBD) affects children and adults, but pediatric onset may have unique characteristics.
  • Understanding the incidence, presentation, and prognosis of childhood IBD is crucial for effective management.

Purpose of the Study:

  • To determine the incidence of IBD in children under 15.
  • To compare the clinical course and prognosis of pediatric-onset IBD with adult-onset IBD.

Main Methods:

  • Analysis of an incidence cohort diagnosed between 1962-1987.
  • Identification of patients with IBD onset before age 15.
  • Comparison of disease characteristics, activity, colectomy rates, and long-term outcomes between pediatric and adult cohorts.

Main Results:

  • Mean incidence of pediatric IBD was 2.2/10(5) (UC: 2.0, CD: 0.2).
  • Children with UC presented with more extensive disease and frequent abdominal pain compared to adults.
  • Colectomy rates and disease activity (remission rates) were similar between pediatric and adult UC patients.
  • Pediatric Crohn's disease (CD) showed no significant differences in presentation, course, or prognosis compared to adult CD.
  • Growth retardation was a significant issue in pediatric CD patients at diagnosis; one UC patient developed colon cancer after 12 years.

Conclusions:

  • Childhood IBD incidence is low, with UC presenting more extensively in children.
  • Pediatric CD course and prognosis mirror adult CD, but growth retardation is a key concern.
  • Long-term outcomes like colectomy rates and disease activity are comparable between pediatric and adult IBD patients.

Related Experiment Videos