[Research progress on the glia cell line-derived neurotrophic factor]

Glia cell line-derived neurotrophic factor (GDNF) is a novel type of neurotrophic factor cloned in 1993. Recent research revealed that it may have potential application in the treatment of Parkinson's disease and motor neuron diseases. This short review summarized the character of the protein, gene structure, tissue distribution, and its physiological functions and pathological implications.