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[Therapeutic strategy for vasospasm. Pharmacologic treatment]
1Clinica Neurochirurgica, Università degli Studi, Genova.
Minerva Anestesiologica
|October 17, 1998
Abstract:
A wide range of pharmacological treatment options for medical management of vasospasm, following SAH, are reported, i.e. calcium-antagonists, 21-amino-steroids, fibrinolytics, vasodilators and CVF (venom of Cobra). Out of them, action mechanisms and clinical experiences are discussed, pointing out that surgical depletion of cisternal clots, hypertension, hypovolemia and hemodilution still represent a golden standard in the management of vasospasm due to SAH.