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Kinase-phosphatase competition regulates Bacillus subtilis development
1Dept of Molecular and Experimental Medicine, Scripps Research Institute, La Jolla, CA 92037, USA. mperego@scripps.edu
Trends in Microbiology
|October 21, 1998
Abstract:
The major regulator of sporulation initiation in Bacillus subtilis is the phosphorelay, a multicomponent signal transduction system. A myriad of signals, both positive and negative, from the environment, cell cycle and metabolism is received and interpreted by the phosphorelay and integrated through the opposing activity of protein kinases and protein aspartate phosphatases to create an extremely sophisticated regulatory network.