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Fatal adverse event secondary to high osmolality contrast agent
R Guharoy1, J Medicis, D Lehmann
1Department of Medicine, University Hospital, State University of New York Health Science Center at Syracuse 13210, USA.
Veterinary and Human Toxicology
|October 21, 1998
Abstract:
Adverse drug events secondary to iodinated contrast agents are of particular concern to all clinicians. Despite the availability of newer agents, the mortality rates remain unchanged. We describe a fatal adverse event secondary to use of the high osmolality agent iothalmate meglumine 30%. A 58-y-old healthy female with no previous history of drug or food allergy had cardiac arrest toward the end of the i.v. infusion of the contrast agent during a CT scan. The patient expired despite aggressive therapeutic measures.