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Waldenström's macroglobulinemia with pulmonary amyloidosis
P Zatloukal1, P Bezdícek, M Schimonová
1Department of Pneumology and Thoracic Surgery, Third Faculty of Medicine, First Department of Tuberculosis and Respiratory Diseases, Pathology and Hematology, First Faculty of Medicine, Charles University, Prague, Czech Republic. zatloukal@mbox.cesnet.cz
Respiration; International Review of Thoracic Diseases
|October 23, 1998
Abstract:
We present a case of AL-type amyloidosis involving pulmonary parenchyma and hilar and mediastinal lymph nodes in a patient with Waldenström's macroglobulinemia. Direct infiltration of pulmonary parenchyma by lymphocytes and plasma cells is an important factor in the etiology and pathogenesis of pulmonary manifestations of the disease. Despite detailed examination, we did not find amyloid depositions in any extrapulmonary site.