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Related Experiment Videos

Lepromatous uveitis diagnosed by iris biopsy

E M Messmer1, M B Raizman, C S Foster

  • 1University Eye Hospital, Munich, Germany.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|October 23, 1998
PubMed
Summary

Ocular leprosy, a rare condition in developed nations, can cause severe eye inflammation. Early diagnosis is crucial, as leprosy should be considered in cases of uveitis and keratitis.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Ocular manifestations of leprosy are uncommon, particularly in developed countries.
  • Leprosy diagnosis typically relies on clinical presentation and skin biopsies.

Observation:

  • A case of bilateral uveitis, glaucoma, and keratitis in a developed country is presented.
  • The patient underwent long-term follow-up for these severe ocular conditions.

Findings:

  • Biopsies of the skin, iris, and aqueous humor revealed numerous Wade-Fite-positive bacilli.
  • These findings confirmed the presence of Mycobacterium leprae, the causative agent of leprosy.

Implications:

  • This case highlights the importance of considering leprosy in the differential diagnosis of unexplained keratitis and uveitis.

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  • Ocular leprosy requires a high index of suspicion, even in regions where it is not endemic.