[The neurotropic activity of peptide immunomodulators]

Four-day monitoring using standard methods of studying free group behavior of animals in an "open field" (Opto-Varimex, USA) showed that all the peptide immunomodulators under study possessed a neuromodulating effect comparable with that of known drugs. They change the character of the circadian rhythms of the animals' motor activity and the dynamics of extinction of the orientation-investigation reaction. In comparison with the control the activity of the drugs under study was distributed as follows: ethymizol > cerebrolysin > thymalin > nootropil > thymogen > T-activin > cortexin > dibazol.