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Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Tannins, flavonol sulfonates, and a norlignan from phyllanthus virgatus
1Graduate Institute of Pharmaceutical Sciences, Taipei Medical College, No. 250, Wu-Hsing St., Taipei, Taiwan, Republic of China, and National Research Institute of Chinese Medicine, No. 155-1, Sec. 2, Li Nung St. Peitou, Taipei, Taiwan, Republi.
Abstract:
Investigation of the constituents of Phyllanthus virgatus has led to the isolation of five new compounds, including a norlignan, 2-(3, 4-methylenedioxybenzyl)-4-(3,4-methylenedioxyphenyl)-3-butyne-1, 2-diol named virgatyne (1); a hydrolyzable tannin, virganin (2); and three flavonoid sulfonates, galangin-8-sulfonate (4), galangin-3-O-beta-D-glucoside-8-sulfonate (5), and kaempferol-8-sulfonate (6). Their structures were established by spectral and chemical methods.
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