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[Immunomorphological characteristics of primary and recurrent breast neoplasms]
N N Volchenko1, L E Zavalishina, I B Shimbireva
1P. A. Herzen Moscow Oncological Institute, Moscow.
Arkhiv Patologii
|October 29, 1998
Abstract:
Primary and recurring breast carcinomas do not differ in the expression of proliferating cell nuclear antigen (PCNA), C-erb-2 oncoprotein, carcinoembryonic antigen and trophoblastic antigen. The content of PCNA and C-erb-2 oncoprotein is twice as high in tumors with an unfavorable prognosis and the frequency of combination of these markers is much higher comparing to tumors with a good prognosis.