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Related Experiment Videos

Yield strain behavior of trabecular bone

D L Kopperdahl1, T M Keaveny

  • 1Department of Mechanical Engineering, University of California, Berkeley 94720-1740, USA. kopper@euler.me.berkeley.edu

Journal of Biomechanics
|October 31, 1998
PubMed
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Trabecular bone remodeling aims for constant safety factors. However, compressive yield strains in bone depend on density, refuting the independence hypothesis, while tensile yield strains remain constant.

Area of Science:

  • Biomechanics
  • Biomaterials Science
  • Orthopedic Research

Background:

  • Bone adaptation theories suggest constant safety factors during habitual loading.
  • This relies on the assumption that yield strains in trabecular bone are independent of apparent density.
  • Investigating this assumption is crucial for understanding bone remodeling and predicting fracture risk.

Purpose of the Study:

  • To test the hypothesis that on-axis yield strains in human vertebral trabecular bone are independent of apparent density.
  • To compare compressive and tensile yield strains in human bone with previously published bovine bone data.
  • To determine the relationship between apparent density and yield strains under axial loading.

Main Methods:

  • Mechanical testing of human vertebral trabecular bone (n=22) and bovine tibial trabecular bone (n=44) specimens.

Related Experiment Videos

  • Measurement of compressive and tensile yield strains under superior-inferior loading.
  • Analysis of yield strains in relation to apparent bone density, controlling for end-artifacts.

    • Main Results:

    • On-axis tensile yield strains were independent of apparent density in both human and bovine bone (p > 0.40).
    • Compressive yield strains were linearly correlated with apparent density in human bone (p < 0.001) and pooled data (p < 0.001).
    • The hypothesis of density independence for compressive yield strains was refuted, though values appeared constant within narrow density ranges.

    Conclusions:

    • On-axis yield strains in trabecular bone are not universally independent of apparent density, particularly under compressive loading.
    • Tensile yield strains appear to be density and site-independent, supporting the constant safety factor hypothesis for tensile loading.
    • Findings challenge existing bone adaptation models and highlight the need to consider density-dependent compressive properties.