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Anaphylactic reaction to bovine serum albumin after embryo transfer
J Wehner-Caroli1, T Schreiner, W Schippert
1Department of Dermatology, Eberhard-Karls-Universität, Tübingen, Germany. joerg.wehner-caroli@med.uni-tuebingen.de
Objective:
To increase the awareness of bovine serum albumin (BSA) sensitivity as a potentially lethal complication during ET.
Design:
Case report.
Setting:
Routine ET in university hospital.
Patient(S):
A 26-year-old woman who was undergoing her first ET.
Intervention(S):
ET with BSA containing standard fluid medium.
Main Outcome Measure(S):
Specific immunoglobulin (Ig) E antibodies and skin tests.
Result(S):
The patient demonstrated increased levels of specific IgE antibodies to BSA and a clearly positive scratch test for BSA.
Conclusion(S):
Anaphylactic reactions to BSA can occur during ET. The risk can be reduced substantially if a detailed medical history is obtained.