Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stress-activated signalling pathways in yeast

W M Toone1, N Jones

  • 1Imperial Cancer Research Fund, PO Box 123, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

Genes to Cells : Devoted to Molecular & Cellular Mechanisms
|November 3, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Psychological and mental health factors involved in nausea and vomiting across pregnancy.

Journal of reproductive and infant psychology·2025
Same author

Systematic review: dorsal bridge plating in distal radius fractures.

Musculoskeletal surgery·2024
Same author

Laryngo- rhino- otologie·2022
Same author

Laryngo- rhino- otologie·2022
Same author

Laryngo- rhino- otologie·2022
Same author

Laryngo- rhino- otologie·2022
Same journal

The Nuclear Export Signal of IκBα Drives RelB Oscillations in the Noncanonical NF-κB Pathway.

Genes to cells : devoted to molecular & cellular mechanisms·2026
Same journal

The SQSTM1 L341V Variant Associated With Sporadic ALS Promotes the Accumulation of Enlarged Ubiquitin-Positive SQSTM1 Bodies.

Genes to cells : devoted to molecular & cellular mechanisms·2026
Same journal

Partial Depletion of SART1 Selectively Induces Mitotic Defects and Cell Death in Cancer Cells.

Genes to cells : devoted to molecular & cellular mechanisms·2026
Same journal

FOXO1 Is Required for Growth and Viability of Cancer-Associated Fibroblasts in Human Breast Carcinomas.

Genes to cells : devoted to molecular & cellular mechanisms·2026
Same journal

Strain-Dependent Functional Variation of a Sex Specific Sox9 Enhancer.

Genes to cells : devoted to molecular & cellular mechanisms·2026
Same journal

An Outflow Tract Myocardium-Specific Enhancer at the Sema3c Locus During Heart Development.

Genes to cells : devoted to molecular & cellular mechanisms·2026
See all related articles

Eukaryotic cells use conserved stress response pathways, like MAP kinase signaling, to alter gene expression and produce protective proteins. This review details these mechanisms in yeast.

Area of Science:

  • Cell Biology
  • Molecular Biology
  • Genetics

Background:

  • Eukaryotic cells possess mechanisms to counteract stress.
  • Stress responses often involve altered gene expression and increased protective proteins.
  • These mechanisms are conserved across species, from yeast to humans.

Purpose of the Study:

  • To review progress in understanding stress-dependent transcriptional changes.
  • To focus on the conserved stress-activated MAP kinase pathways.
  • To detail these stress response mechanisms specifically in yeast.

Main Methods:

  • Review of existing literature on stress response pathways.
  • Analysis of conserved signaling mechanisms.
  • Focus on yeast as a model organism.

Related Experiment Videos

Main Results:

  • Stress signals are transduced from the cell surface to the nucleus via signaling pathways.
  • Stress-activated MAP kinase pathways are crucial for stress response.
  • Pathway activation leads to increased transcription factor activity and gene expression.

Conclusions:

  • Stress response mechanisms in yeast are highly conserved.
  • MAP kinase pathways play a central role in mediating cellular adaptation to stress.
  • Understanding these pathways in yeast provides insights into fundamental eukaryotic stress biology.