Related Experiment Videos
Signal transduction: fast lane to transcriptional activation
1MRC Laboratory of Molecular Biology Hills Road, Cambridge, CB2 2QH, UK.
Current Biology : CB
|November 4, 1998
Abstract:
Two newly reported structures of homodimeric 'STAT' transcription factors bound to DNA reveal at atomic resolution the elegant mechanism through which kinase activity at the cell membrane can be transduced into transcriptional activation within the cell nucleus.