Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic urticaria

A Leznoff1

  • 1Division of Clinical Immunology, St Michael's Hospital, Toronto.

Canadian Family Physician Medecin De Famille Canadien
|November 7, 1998
PubMed
Summary
This summary is machine-generated.

Most chronic urticaria cases are autoimmune, not allergic. Understanding this autoimmune pathophysiology guides effective management strategies for this common skin condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hyposensitization therapy.

Canadian family physician Medecin de famille canadien·2011
Same author

Idiopathic environmental intolerances: results of challenge studies.

Occupational medicine (Philadelphia, Pa.)·2000
Same author

Cataract extraction by phacoemulsification in a sympathizing eye.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2000
Same author

Re: Davidoff et al. Development of multiple chemical sensitivities in laborers after acute gasoline fume exposure in an underground tunnelling operation.

Archives of environmental health·1999
Same author

Provocative challenges in patients with multiple chemical sensitivity.

The Journal of allergy and clinical immunology·1997
Same author

Cyclosporine in the treatment of nonmicrobial inflammatory ophthalmic disease.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·1993
Same journal

Impact of virtual case conferences between primary care clinicians and an interdisciplinary chronic pain clinic.

Canadian family physician Medecin de famille canadien·2026
Same journal

Canadian family physician Medecin de famille canadien·2026
Same journal

Predictors of high-performing family medicine clinics: Prospective cohort study in Alberta.

Canadian family physician Medecin de famille canadien·2026
Same journal

Acetylsalicylic acid use for artial fibrillation and bleeding risk.

Canadian family physician Medecin de famille canadien·2026
Same journal

Clinical practice guidelines: Important tools to teach the art of medicine.

Canadian family physician Medecin de famille canadien·2026
Same journal

Paratonia in advanced dementia: Challenges and evidence-based interventions.

Canadian family physician Medecin de famille canadien·2026
See all related articles

Area of Science:

  • Immunodermatology
  • Autoimmunity
  • Urticaria Pathophysiology

Background:

  • Chronic urticaria (CU) presents as recurrent hives and angioedema.
  • Recent evidence suggests an autoimmune basis for a significant proportion of CU cases.
  • Understanding the underlying pathophysiology is crucial for effective patient management.

Purpose of the Study:

  • To review the pathophysiology of chronic urticaria, emphasizing recent autoimmune evidence.
  • To recommend appropriate diagnostic and management strategies for chronic urticaria.

Main Methods:

  • Extensive literature review including MEDLINE searches.
  • Prioritization of recent articles on autoimmunity and chronic urticaria.
  • Inclusion of previous studies on pathophysiology supporting current evidence.

Related Experiment Videos

Main Results:

  • Histopathology and immunohistology confirm most chronic urticaria is autoimmune.
  • Allergic and other causes are uncommon but require investigation for potential cures.
  • Management of autoimmune urticaria is guided by pathogenesis and clinical trial data.

Conclusions:

  • The majority of chronic urticaria cases are autoimmune in origin.
  • Consideration of uncommon allergic or other etiologies remains important.
  • Evidence-based management protocols are essential for autoimmune chronic urticaria.