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Cough during emergence from isoflurane anesthesia
1Kangnam St. Mary's Hospital, Seoul, Korea.
Anesthesia and Analgesia
|November 7, 1998
Summary
Most patients cough when waking from anesthesia, regardless of smoking history or albuterol treatment. Coughing during emergence from anesthesia is common but not influenced by smoking or albuterol use.
Area of Science:
- Anesthesiology
- Respiratory Medicine
- Pharmacology
Background:
- Coughing during emergence from anesthesia is a common occurrence.
- Factors influencing emergence cough, such as smoking history and bronchodilator use, require further investigation.
Purpose of the Study:
- To evaluate the impact of smoking history on cough frequency and amplitude during emergence from anesthesia.
- To determine the efficacy of albuterol treatment in mitigating cough during the emergence period.
Main Methods:
- A randomized controlled trial involving 68 patients undergoing anesthesia.
- Patients received either albuterol or a placebo via metered-dose inhaler before anesthesia induction.
- Cough frequency, amplitude, and end-tidal isoflurane concentration at cough onset were recorded during emergence.
Main Results:
- Coughing occurred in 52 of 68 patients during emergence.
- No significant difference in cough incidence or characteristics was observed between smokers and nonsmokers.
- Albuterol treatment did not significantly alter the frequency or amplitude of coughs.
Conclusions:
- Cough is a frequent event during emergence from general anesthesia.
- Neither smoking history nor albuterol administration impacts the incidence or severity of emergence cough.
- Patients are unlikely to experience cough at end-tidal isoflurane concentrations above 0.6%.